Nsp12-IN-2

Overview

Nsp12-IN-2 (Compound 8), the triphosphate metabolite of 4'-thiouridine ( HY-W113081 ), is a SARS-CoV-2 Nsp12 inhibitor. Nsp12-IN-2 inhibits the RNA-dependent RNA polymerase (RdRp) activity of the SARS-CoV-2 Nsp12-Nsp7-Nsp8 complex, terminates RNA synthesis and also blocks the RNAylation and NMPylation of Nsp9. Nsp12-IN-2 is promising for research of infections caused by SARS-CoV-2, other coronaviruses, and other RNA viruses.

Application

Products | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > SARS-CoV | Products > Signaling Pathways > Virus Protease | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-174439
• CAS No.: 667882-55-5
• Molecular Formula: C9H12N2Na3O14P3S
• Molecular Weight: 566.15
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source