Bumetanide sodium, a highly potent loop diuretic, is a Na + -K + -Cl + cotransporter ( NKCC ) blocker. Bumetanide sodium is a selective NKCC1 inhibitor, and also inhibits NKCC2, with IC 50 s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > NKCC
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