Fidaxomicin (OPT-80), a macrocyclic antibiotic , is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti- Clostridium difficile activity (MIC 90 =0.12 μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research.
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