Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase ( OvCHT1 ) inhibitor with an IC 50 of 1.6 μM and a K i of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing.
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