S118

Overview

S118 is an orally active sphingosine-1-phosphate receptor 2 ( S1P 2 receptor ) inhibitor. S118 prevents the binding of the S1P 2 receptor to dapper1 (Dpr1), reduces the accumulation of β-catenin and blocks the nuclear translocation of the S1P 2 receptor, thereby inhibiting inflammation, fibrosis, and epithelial-mesenchymal transition (EMT) and exerting anti-idiopathic pulmonary fibrosis (IPF) activity. S118 is promising for research of idiopathic pulmonary fibrosis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > β-catenin

Product Information

• Catalog No.: HY-176057
• CAS No.: 2677041-36-8
• Molecular Formula: C19H14Cl2FN7O
• Molecular Weight: 446.27
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source