CDK2-IN-46 (compound 5g) is a selective CDK2 inhibitor with an IC 50 of 0.3 nM. CDK2-IN-46 has a selectivity of >200-fold for CDK1 , CDK7 , CDK9 , CDK4 , and CDK6 . CDK2-IN-46 shows improves rat and cyno pharmacokinetic profiles.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > CDK
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