Antibacterial agent 287 (Compound 26), a derivative of Deoxynybomycin ( HY-116926 ), is an antibacterial agent. Antibacterial agent 287 has potent antibacterial activity against a variety of Gram-negative bacterium with MIC s of 0.5, 0.5 and 0.06 μg/mL for WT S. aureus , WT E. coli and E. coli ΔtolC , respectively. Antibacterial agent 287 can be used for multidrug-resistant (MDR) bacterium infections research.
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