Lithocholic amide-C2-N(didecane)

Overview

Lithocholic amide-C2-N(didecane) (Compound LC10) is a Lithocholic acid ( HY-B0172 ) analogue. Lithocholic amide-C2-N(didecane) can form lipid nanoparticles spontaneously in the aqueous milieu, permeate through the skin, penetrate the deeper dermal layers, and exert anti-inflammatory effects against psoriasis-like chronic skin inflammations. Lithocholic amide-C2-N(didecane) can inhibit abnormal proliferation of keratinocytes, downregulate the mRNA expression of the psoriasis-associated receptor EphA2 and reduce serum levels of multiple pro-inflammatory factors such as IL-1α , IL-1β , and IFN-γ by inhibiting activation of the Th17/Th2 inflammatory pathway.

Application

Products | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Skin Inflammation | Products > Disease Areas > Psoriasis | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > Ephrin Receptor | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-178721
• CAS No.: 2768690-22-6
• Molecular Formula: C46H86N2O2
• Molecular Weight: 699.19
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source