TJN-331

Overview

TJN-331 is a potent and orally active TGF-β1 Inhibitor. TJN-331 ameliorates anti-glomerular basement membrane (GBM) nephritis in rats by inhibitng TGF-β1 production, thereby reducing extracapillary proliferation in glomeruli. TJN-331 inhibits mesangial expansion in experimental IgA nephropathy in ddY mice. TJN-331 can be used for the research of nephritis and IgA nephropathy.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Renal Disease | Products > Disease Areas > Genitourinary Inflammation | Products > Disease Areas > Nephritis | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > TGF-β Receptor

Product Information

• Catalog No.: HY-178850
• CAS No.: 219964-53-1
• Molecular Formula: C19H22N2O3
• Molecular Weight: 326.39
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source