NS2B/NS3-IN-9

Overview

NS2B/NS3-IN-9 (Compound 73) is a broad-spectrum, non-competitive anti- Orthoflavivirus lipopeptide inhibitor targeting the NS2B-NS3 protease. NS2B/NS3-IN-9 exhibits IC 50 values for Dengue virus DENV2 NS2B-NS3 , West Nile virus WNV NS2B-NS3 , and Zika virus ZIKV NS2B-NS3 of 2.4, 7.2, and 1.9 μM, respectively. NS2B/NS3-IN-9 also exhibits antiviral activity at the cellular level against DENV2, WNV, and ZIKV, with EC 50 values of 4.1, 4.9, and 5.0 μM, respectively. NS2B/NS3-IN-9 has no significant toxicity to cells. NS2B/NS3-IN-9 can be used for the study of anti-Orthoflavivirus.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Virus Protease | Products > Signaling Pathways > Flavivirus | Products > Signaling Pathways > Dengue Virus

Product Information

• Catalog No.: HY-179013
• CAS No.: 812683-94-6
• Molecular Formula: C34H67N7O5
• Molecular Weight: 653.94
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source