SLC6A19-IN-3 (Compound 83-P1-P2) is a potent, selective and orally active SLC6A19 inhibitor with an IC 50 of 28 nM. SLC6A19-IN-3 can block SLC6A19-mediated transmembrane transport of phenylalanine, reducing intestinal absorption of phenylalanine from food and renal tubular reabsorption of phenylalanine. SLC6A19-IN-3 can be used for the research of metabolic disease , such as phenylketonuria.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Amino Acid/Protein Metabolism | Products > Disease Areas > Phenylketonuria | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Amino acid Transporter
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