H36-E4

H36-E4
  • CAS No.:688310-17-0
  • Grade:98.57%
  • Formula:C10H15N5O3
  • M.W.:253.26
  • Solvent:≥ 5 mg/mL (19.74 mM); Clear solution

Overview

H36-E4 is a WW domain containing E3 ubiquitin 27 protein ligase 2 ( WWP2 ) inhibitor with a K D of 6.25 μM. H36-E4 inhibits WWP2 expression, restores the succinate dehydrogenase complex subunit C (SDHC) level, and defers the acute kidney injury (AKI)-to-chronic kidney disease (CKD) transition in unilateral kidney ischemia-reperfusion (UIR) mice. H36-E4 can be used for AKI-to-CKD transition research.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Renal Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > E1/E2/E3 Enzyme

Product Information

  • Catalog No.: HY-180107
  • CAS No.: 688310-17-0
  • Molecular Formula: C10H15N5O3
  • Molecular Weight: 253.26
  • Purity: 98.57%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 5 mg/mL (19.74 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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