H111-H7

H111-H7
  • CAS No.:220965-54-8
  • Grade:98.14%
  • Formula:C13H10ClNO3S2
  • M.W.:327.81

Overview

H111-H7 is a WW domain containing E3 ubiquitin 27 protein ligase 2 ( WWP2 ) inhibitor with a K D of 717 nM. H111-H7 inhibits WWP2 expression, restores the succinate dehydrogenase complex subunit C (SDHC) level, and defers the acute kidney injury (AKI)-to-chronic kidney disease (CKD) transition in unilateral kidney ischemia–reperfusion (UIR) mice. H111-H7 can be used for AKI-to-CKD transition research.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Renal Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > E1/E2/E3 Enzyme

Product Information

  • Catalog No.: HY-180108
  • CAS No.: 220965-54-8
  • Molecular Formula: C13H10ClNO3S2
  • Molecular Weight: 327.81
  • Purity: 98.14%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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