CAI0019

CAI0019
  • CAS No.:2446169-48-6
  • Grade:98.14%
  • Formula:C11H18N4O3S2
  • M.W.:318.42
  • Solvent:≥ 1.25 mg/mL (3.93 mM); Clear solution

Overview

CAI0019 is an orally active α-carbonic anhydrase inhibitor based on the Acetazolamide ( HY-B0782 ) framework. CAI0019 exhibits narrow-spectrum antibiofilm activity, with its MIC 50 being 0.094 μM and MIC 90 being 0.39 μM. CAI0019 selectively inhibits Enterococcus in a septic peritonitis mouse model, without affecting most intestinal commensal bacteria.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Others | Products > Research Areas > Infection | Products > Signaling Pathways > Carbonic Anhydrase | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Drug Derivative

Product Information

  • Catalog No.: HY-180542
  • CAS No.: 2446169-48-6
  • Molecular Formula: C11H18N4O3S2
  • Molecular Weight: 318.42
  • Purity: 98.14%
  • Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 1.25 mg/mL (3.93 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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