CAI0019 is an orally active α-carbonic anhydrase inhibitor based on the Acetazolamide ( HY-B0782 ) framework. CAI0019 exhibits narrow-spectrum antibiofilm activity, with its MIC 50 being 0.094 μM and MIC 90 being 0.39 μM. CAI0019 selectively inhibits Enterococcus in a septic peritonitis mouse model, without affecting most intestinal commensal bacteria.
Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Others | Products > Research Areas > Infection | Products > Signaling Pathways > Carbonic Anhydrase | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Drug Derivative
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.