2,5-DIDEOXY-2,5-IMINO-D-MANNITOL

CAS No.：59920-31-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Basic information

Product Name:	2,5-DIDEOXY-2,5-IMINO-D-MANNITOL
Synonyms:	2R,5R-BIS(HYDROXYMETHYL)-3R,4R-DIHYDROXYPYRROLIDINE;2,5-DIDEOXY-2,5-IMINO-D-MANNITOL;DMDP;2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine;(2R,5R)-bis(hydorxymethyl)-(3R,4R)-dihydroxypyrr;(2R,5R)-BIS(HYDORXYMETHYL)-(3R,4R)-DIHY DROXYPYRROL;2,5-Pyrrolidinedimethanol, 3,4-dihydroxy-, (2R,3R,4R,5R)-;2,5-Dideoxy-2,5-imino-L-mannitol
CAS:	59920-31-9
MF:	C6H13NO4
MW:	163.17
EINECS:	633-130-7
Product Categories:	Carbohydrates & Derivatives;All Inhibitors;Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Glycosidase Inhibitors;Inhibitors
Mol File:	59920-31-9.mol

2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Chemical Properties

Melting point	101-103°C
storage temp.	2-8°C
solubility	Methanol (Slightly), Water (Slightly)
form	Solid
color	Off-White to Pale Yellow
Stability:	Hygroscopic
CAS DataBase Reference	59920-31-9

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
HS Code	29400090

MSDS Information

Provider	Language
SigmaAldrich	English

2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Usage And Synthesis

Chemical Properties	Off-White Solid
Uses	A glucosidase inhibitor
Uses	Many pyrrolidines are powerful inhibitors of glycohydrolases, enzymes responsible for cleavage of glycosidic bonds, glycoprotein processing and the gastrointestinal breakdown of dietary carbohydrates. These compounds are charged at physiological pH and are believed to associate with acidic amino acids at the active site. Inhibition of glycohydrolases could be of therapeutic value for the treatment of viral infections, cancer, diabetes, and obesity.
Uses	A glucosidase inhibitor.

2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Preparation Products And Raw materials

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