Z3071585108 is a small molecule binder of the LAG-3 D1 domain with K d values measured for the MST-TRIC channel and spectral shift detection of 59.2 and 56.1 μM respectively. Z3071585108 partially inhibits the binding of LAG-3 to MHCII, with an EC₅₀ of 42.9 μM. Z3071585108 can be used for the study of small molecule immunotherapies targeting LAG-3 .
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Immunomodulation | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > LAG-3
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