BD-1063-d 8 dihydrochloride

Overview

BD-1063-d 8 dihydrochloride is the deuterium labeled BD1063 dihydrochloride ( HY-18101A ). BD-1063 dihydrochloride is a selective σ-1 receptor antagonist with inhibitory activity against TRPC5 and TRPM3 . BD-1063 dihydrochloride exerts anti-hyperalgesic and anti-allodynic effects by inhibiting sustained calcium influx mediated by TRPC5 and TRPM3, and reverses the effects of Carrageenan ( HY-125474 ). BD-1063 dihydrochloride also significantly reduces excessive ethanol self-administration behavior. BD-1063 dihydrochloride is widely used in studies on the mechanisms underlying neuropathic pain, inflammatory hyperalgesia, and alcohol abuse and dependence.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Sigma Receptor | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-18101S
• CAS No.: 1246819-69-1
• Molecular Formula: C13H10D8Cl2N2
• Molecular Weight: 281.25
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source