IRBM-Z-1

Overview

IRBM-Z-1 is a non-competitive inhibitor of Zika virus ( ZIKV ) NS2B-NS3 protease, with an IC 50 of 1.8 μM. IRBM-Z-1 also exhibits inhibitory activity against the NS2B-NS3 proteases of T156I-mutated dengue virus 2 ( DENV2 ) and West Nile virus ( WNV ), with IC 50 values of 3.9 μM and 4.7 μM, respectively. IRBM-Z-1 inhibits ZIKV replication, attenuates virus-induced cytopathic effects. IRBM-Z-1 is applicable to research related to ZIKV infection .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Virus Protease | Products > Signaling Pathways > Flavivirus

Product Information

• Catalog No.: HY-181990
• CAS No.: 67629-86-1
• Molecular Formula: C19H17F3N4O2
• Molecular Weight: 390.36
• Purity: 98.61%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source