TPα/β antagonist-1 is a TXA2 receptor α (TPα) and TPβ antagonist with IC 50 s of 1.52 nM and 0.79 nM, respectively. TPα/β antagonist-1 inhibits U-46619 ( HY-108566 )-induced intracellular calcium mobilization, and imhibits platelet aggregation. TPα/β antagonist-1 can be used for the research of cardiovascular disease .
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Prostaglandin Receptor
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