Diclofensine-d 3 (hydrochloride)

Overview

Diclofensine-d 3 (Ro-8-4650-d 3 ) hydrochloride is the deuterium labeled Diclofensine hydrochloride. Diclofensine hydrochloride is an orally active neuronal monoamine uptake inhibitor. Diclofensine hydrochloride blocks the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC 50 values of 0.74, 2.3 and 3.7 nM, respectively. Diclofensine hydrochloride potentiates norepinephrine-induced hypertension and attenuates Tyramine ( HY-W007606 )-induced hypertension. Diclofensine hydrochloride produces psychostimulant and mood-elevating effects without causing sudden disappearance or withdrawal reactions. Diclofensine hydrochloride can be used in the research of moderate to severe depression.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Dopamine Transporter | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-18610S
• CAS No.: 1794780-41-8
• Molecular Formula: C17H15D3Cl3NO
• Molecular Weight: 361.71
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source