PFI-2

Overview

PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride, a chemical probe, is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC 50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC 50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis.

Application

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Product Information

• Catalog No.: HY-18627
• CAS No.: 1627676-59-8
• Molecular Formula: C23H25F4N3O3S
• Molecular Weight: 499.52
• Purity: 99.68%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source