FIT-039

Overview

FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC 50 of 5.8 μM for CKD9/cyclin T1 . FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 ( IC 50 of 0.69 μM), HSV-2 , human adenovirus , and human CMV . FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses .

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Viral Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > CDK | Products > Signaling Pathways > HSV | Products > Signaling Pathways > CMV | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-18944
• CAS No.: 1113044-49-7
• Molecular Formula: C17H18FN3S
• Molecular Weight: 315.41
• Purity: 99.56%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (7.93 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source