MEN-91507 is an orally active cysteinyl leukotriene receptor 1 ( CysLTR1 ) receptor antagonist. MEN-91507 behaves as insurmountable antagonist of Leukotriene D4 ( HY-113456 )-induced calcium transients, with a pK b of 10.25. MEN-91507 can inhibit Leukotriene D4 -induced bronchoconstriction and microvascular leakage in guinea-pigs. MEN-91507 can be used for the researches of inflammation, immunology.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Leukotriene Receptor
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