CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID

CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID
  • CAS No.:54162-90-2

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID Basic information
Product Name:CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID
Synonyms:CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID;CIS-6-AMINO-CYCLOHEX-3-ENECARBOXYLIC ACID;cis-2-Amino-4-cyclohexene-1-carboxylic acid, 98+%;3-Cyclohexene-1-carboxylicacid,6-amino-,(1R,6S)-rel-(9CI);3-Cyclohexene-1-carboxylic acid, 6-amino-, (1R,6S)-rel-;CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID USP/EP/BP;6-Aminocyclohex-3-ene-COOH(S,R);(1S,6R)-6-aminocyclohex-3-ene-1-carboxylic acid
CAS:54162-90-2
MF:C7H11NO2
MW:141.17
EINECS:
Product Categories:AMINOACID
Mol File:54162-90-2.mol
CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID Chemical Properties
Melting point 196-199 °C
Boiling point 258.21°C (rough estimate)
density 1.1522 (rough estimate)
refractive index 1.5026 (estimate)
CAS DataBase Reference54162-90-2
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-20/21/22-43
Safety Statements 36/37/39-26-36/37
HS Code 2922498590
MSDS Information
ProviderLanguage
ACROS English
CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID Usage And Synthesis
Chemical PropertiesBEIGE FINE POWDER
Purification MethodsPurify the free amino-acid by dissolving it in H2O and passing it through a Dowex 50W (acid form) column and eluting with 1M aqueous NH4OH. The eluate is evaporated (in vacuo) and the residue is dissolved in H2O. Me2CO is added to turbidity, cooled at 0o and the colourless crystals of the amino-acid are collected and dried in vacuo [Bernáth et al. Tetrahedron 41 1315 1958, cf Mazza & Crapetta Gazzetta 57 297 1927]. In earlier work, it was recrystallised from aqueous EtOH and had reported melting points of 265-265o [Kricheldorf Justus Liebigs Ann Chem 1378 1975] and 269-271o [Marconi & Mazzochi J Org Chem 31 1372 1966]. The hydrochloride [57266-56-5] M 177.6 has m 210-213o and the methyl ester hydrochloride [52766-61-2] has m 85-87o (from Et2O). The trans-(±)-(1RS,2RS)-amino-acid [97945-19-2] crystallises from aqueous Me2CO with m 267-269o. [Beilstein 14 II 203.]
CIS-2-AMINO-4-CYCLOHEXENE-1-CARBOXYLIC ACID Preparation Products And Raw materials

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