Tanimilast (CHF-6001) is an orally active and selective phosphodiesterase 4 inhibitor ( IC 50 =0.026 nM) with robust anti-inflammatory activity and suitable for topical pulmonary administration. Tanimilast increases cellular cAMP levels, and inhibits NF-κB signaling pathway. Tanimilast is used for the research of obstructive lung diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > CXCR | Products > Signaling Pathways > CCR | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Interleukin Related
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