RCM-1 is a forkhead box M1 (FOXM1) inhibitor with an EC 50 of 0.72 μM in U2OS cells. RCM-1 blocks the nuclear localization and increased the proteasomal degradation of FOXM1 . RCM-1 can be used for asthma and other chronic airway diseases research.
Products | Products > Disease Areas > Asthma | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lower Respiratory Inflammation | Products > Disease Areas > Respiratory Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > FOXM1 | Products > Signaling Pathways > DNA/RNA Synthesis
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