Exatecan intermediate 9

Overview

Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan ( HY-13631 ). Exatecan (DX-8951) is a common toxin component in ADC preparation ( ADC Cytotoxin ) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-43565
• CAS No.: 2290562-59-1
• Molecular Formula: C26H24FN3O5
• Molecular Weight: 477.48
• Purity: 99.98%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source