Bafetinib

Overview

Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins ( Bim , Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family , and induces apoptosis of Ph + leukemia cells. Bafetinib has antitumor activity.

Application

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Product Information

• Catalog No.: HY-50868
• CAS No.: 859212-16-1
• Molecular Formula: C30H31F3N8O
• Molecular Weight: 576.62
• Purity: 99.02%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.34 mM); Clear solution
• Availability: In-stock

Source

Original product source