Gefitinib-d 3

Overview

Gefitinib-d 3 (ZD1839-d 3 ) is the deuterium labeled Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth ( IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy . Gefitinib has antitumour activity.

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-50895S2
• CAS No.: 1173976-40-3
• Molecular Formula: C22H21D3ClFN4O3
• Molecular Weight: 449.92
• Purity: 98.39%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source