25-Hydroxytachysterol3 is the metabolite of Vitamin D3 ( HY-15398 ). 25-Hydroxytachysterol3 inhibits the proliferation of epidermal keratinocytes and dermal fibroblasts, stimulates the expression of differentiation- and antioxidant-related genes in keratinocytes. 25-Hydroxytachysterol3 activates vitamin D receptor ( VDR ) and aryl hydrocarbon receptor ( AhR ), liver X receptor α/β ( LXR α/β ) and peroxisome proliferator-activated receptor γ ( PPARγ ), stimulates the expression of CYP24A1.
Products | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Others | Products > Signaling Pathways > VD/VDR | Products > Signaling Pathways > Aryl Hydrocarbon Receptor | Products > Signaling Pathways > LXR | Products > Signaling Pathways > PPAR
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