Lenalidomide-d 4

Overview

Lenalidomide-d 4 (CC-5013-d 4 ) is deuterium labeled Lenalidomide. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3 , by the CRBN-CRL4 ubiquitin ligase . Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.

Application

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Product Information

• Catalog No.: HY-A0003S3
• CAS No.: 1130061-52-7
• Molecular Formula: C13H9D4N3O3
• Molecular Weight: 263.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source