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| Polyinosinic-polycytidylic acid sodium salt Basic information |
| Polyinosinic-polycytidylic acid sodium salt Chemical Properties |
| storage temp. | −20°C | | solubility | H2O: soluble10mg/mL | | form | lyophilized powder |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | TR0175000 |
| Polyinosinic-polycytidylic acid sodium salt Usage And Synthesis |
| Uses | TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic–polycytidylic acid sodium salt is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
| | Uses | Polyinosinic Acid & Polycytidylic Acid Sodium Salt (double-stranded) is a TLR3 (Toll-like receptor 3) agonist. | | Biological Activity | Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis. |
| Polyinosinic-polycytidylic acid sodium salt Preparation Products And Raw materials |
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