Other grades of this product :
| Timosaponin A-III Basic information |
| Timosaponin A-III Chemical Properties |
| Melting point | 317-322 °C | | Boiling point | 862.8±65.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | pka | 12.85±0.70(Predicted) | | form | White to off white solid. |
| Timosaponin A-III Usage And Synthesis |
| Uses | Timosaponin A3 suppresses certain human tumor processes and has the potential to be developed as an anticancer agent. Reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. Induction of mitochondrial-dependent apoptosis in HepG2 human hepatocellular carcinoma cells.Timosaponin A3 is a potent inhibitor of U46619, that induces rat platelet aggregation and exhibited superior selectivity for the TP receptor vs. other G protein-coupled receptors and a PKC activator. |
| Timosaponin A-III Preparation Products And Raw materials |
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