Pefloxacin (Standard) (Pefloxacinium (Standard)) is the analytical standard of Pefloxacin ( HY-B0147 ). This product is intended for research and analytical applications. Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic . Pefloxacin blocks DNA replication by inhibiting DNA gyrase . Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC 50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli , Pseudomonas aeruginosa , and Bacteroides fragilis with MIC 90 s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti- Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.
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