Nicotinamide hydrochloride is a form of vitamin B3 or niacin. Nicotinamide hydrochloride inhibits SIRT2 activity ( IC 50 : 2 μM). Nicotinamide hydrochloride also inhibits SIRT1 . Nicotinamide hydrochloride increases cellular NAD + , ATP, ROS levels. Nicotinamide hydrochloride inhibits tumor growth and improves survival. Nicotinamide hydrochloride also has anti- HBV activity.
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