Carmofur (HCFU) is a rat recombinant acid ceramidase inhibitor with an IC 50 of 29 nM. Carmofur is also a protease inhibitor of SARS-CoV-2 main protease ( Mpro ), fatty acid amide hydrolase ( FAAH ) and N-acylethanolamine acid amidase ( NAAA ). Carmofur has anti-cancer, anti-inflammatory and anti-virus activities, and can be used for the study of COVID-19 and acute lung injury (ALI).
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