Nafamostat, an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat has anticancer and antivirus effect. Nafamostat induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 ( TNFR1 ). Nafamostat can be used in the development of the pathological thickening of the arterial wall.
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