Albiflorin

Albiflorin
  • CAS No.:39011-90-0
Other grades of this product :
Albiflorin Basic information
Product Name:Albiflorin
Synonyms:(1R,3R,4R,6S,9S)-9-[(Benzoyloxy)Methyl]-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-Methyl-7-oxatricyclo[4.3.0.03,9]nonan-8-one;Albiflorin, froM Paeonia lactiflora;ALBIFLORIN;Albiflorin 9-((Benzoyloxy)methyl)-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclononan-8-one;Albiflorin std;9-((Benzoyloxy)methyl)-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methyl-7-oxatricyclononan-8-one;[(benzoyloxy)methyl]-1-(β-D-glucopyranosyloxy)-;4-hydroxy-6-methyl-, (1R, 3R, 4R, 6S)-
CAS:39011-90-0
MF:C23H28O11
MW:480.46
EINECS:
Product Categories:The group of Paeoniflorin;Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:39011-90-0.mol
Albiflorin Chemical Properties
Boiling point 722.1±60.0 °C(Predicted)
density 1.58±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
pka12.84±0.70(Predicted)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29389090
MSDS Information
Albiflorin Usage And Synthesis
Biological FunctionsAlbiflorin is a natural product isolated from Paeoniae Radix. It enhances mitochondrial function to suppress antimycin A-induced oxidative damage via the preservation of cytochrome c and cardiolipin. Also it may reduce or prevent osteoblast degeneration in osteoporosis.
Biological ActivityAlbiflorin is a natural phenolic compound that has been shown to be an inhibitor of toll-like receptor (TLR) 4.
in vitroAlbiflorin can modulate the TLR-induced inflammatory response by inhibiting the production of proinflammatory cytokines, such as IL-6, IL-8, and TNF-α. This compound also inhibits matrix metalloproteinase activity in tubulointerstitial injury, leading to decreased interstitial inflammation and proteinuria. Albiflorin has been shown to be effective at low doses in experimental models of rheumatoid arthritis. It is believed that this effect may be due to its ability to inhibit TLR4 expression or activation.
Albiflorin Preparation Products And Raw materials

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