Prothionamide -d 5 is deuterium labeled Prothionamide ( HY-B0306 ). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a K m value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA . Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae . Prothionamide is used in the research of tuberculosis and leprosy.
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Bacterial
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