(R)-Ofloxacin is the dextrorotatory enantiomer of Ofloxacin ( HY-B0125 ) and is an orally effective fluoroquinolone antibiotic . (R)-Ofloxacin can inhibit the activity of bacterial DNA topoisomerase II, interfere with bacterial DNA replication and repair, and exert a bactericidal effect. (R)-Ofloxacin has a broad-spectrum antibacterial activity and has inhibitory effects on both Gram-negative and Gram-positive bacteria.
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