epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril ( HY-B0368 ) and an inhibitor of metallo-β-lactamases ( MBLs ). The IC 50 values of epi-D-Captopril against NDM-1 , IMP-1 , and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. epi-D-Captopril is expected to be used in the research of diseases caused by MBLs-related drug-resistant bacterial infections.
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