Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I 1 -R) agonist. Moxonidine activates imidazoline I 1 receptors and α 2 adrenoceptors , affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis.
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