Probucol (DH-581) is an anti-hyperlipidemic agent. Probucol activates glutathione peroxidase . Probucol promotes low density lipoprotein (LDL) catabolism, inhibits ABCA1-dependent cholesterol efflux, and decreases HDL-C levels. Probucol also has anti-inflammatory, antioxidant and neuroprotective properties. Probucol can be used for researches on bone, cardiovascular, cancer , neurological, and metabolism-related diseases.
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