L-NIO DIHYDROCHLORIDE

CAS No.：36889-13-1

Other grades of this product :

L-NIO DIHYDROCHLORIDE Basic information

Product Name:	L-NIO DIHYDROCHLORIDE
Synonyms:	L-NIO;L-NIO, 2HCL;n(g)-iminoethylornithine;NG-(1-IMINOETHYL)-L-ORNITHINE HYDROCHLORIDE;N5-(1-IMINOETHYL)-L-ORNITHINE DIHYDROCHLORIDE;N(5)-(1-IMINOETHYL)-L-ORNITHINE HCL;N5-(1-IMINOETHYL)-L-ORNITHINE HYDROCHLORIDE;L-N5-(I-IMINOETHYL)ORNITHINE HYDROCHLORI DE POTENT IRREVERSIBLE N
CAS:	36889-13-1
MF:	C7H15N3O2
MW:	173.21
EINECS:
Product Categories:	Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Nitric Oxide Reagents;Nitric Oxide
Mol File:	36889-13-1.mol

L-NIO DIHYDROCHLORIDE Chemical Properties

Melting point	225-226°C
storage temp.	-20°C
solubility	Methanol (Slightly), Water (Slightly)
form	Solid
color	White to Off-White
Stability:	Hygroscopic

Safety Information

Safety Statements	24/25
HS Code	29224985

MSDS Information

Provider	Language
ACROS	English

L-NIO DIHYDROCHLORIDE Usage And Synthesis

Description	L-NIO is a non-selective inhibitor of all NOS isoforms. The K_i values for nNOS (rat), eNOS (bovine), and iNOS (mouse) are 1.7, 3.9, and 3.9 μM, respectively. L-NIO inhibits endothelial-dependent relaxation induced by acetylcholine in rat aortic rings and hypotensive responses to acetylcholine and bradykinin.
Chemical Properties	White Crystalline Solid
Uses	A potent and reversible inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells
Biological Activity	Potent inhibitor of endothelial NO synthase (IC 50 = 500 nM). Also inhibits iNOS and nNOS. Active in vivo .

L-NIO DIHYDROCHLORIDE Preparation Products And Raw materials

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