Lomefloxacin (SC47111A) is an orally active difluoroquinolone antibiotic . Lomefloxacin prevents DNA supercoiling and replication by inhibiting bacterial topoisomerase II . Lomefloxacin induces ROS production and Apoptosis . Lomefloxacin has broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria. Lomefloxacin has anticancer effects against melanoma. Lomefloxacin can be used in the study of systemic bacterial infections (such as Salmonella typhimurium infections), skin and melanoma .
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Infection | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Antibiotic
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