Product

H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH

CAS No.：34273-12-6

Other grades of this product :

H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Basic information

Product Name:	H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH
Synonyms:	ANGIOTENSIN 1/2 (1-9);ANGIOTENSIN (1-9);ANGIOTENSIN I (1-9);H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH;H2N-DRVYIHPFH-OH;DRVYIHPFH;Des-Leu angiotensin I【human】;L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe-L-His-OH
CAS:	34273-12-6
MF:	C56H78N16O13
MW:	1183.32
EINECS:
Product Categories:	SignalTransduction;peptide
Mol File:	34273-12-6.mol

H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Chemical Properties

storage temp.	-15°C
solubility	≥118.3 mg/mL in DMSO; insoluble in EtOH; ≥51 mg/mL in H2O
form	solid

Safety Information

HS Code

29371900

MSDS Information

H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Usage And Synthesis

Chemical Properties	White powder
Biological Activity	angiotensin i/ii (1-9) is a peptide (asp-arg-val-tyr-ile-his-pro-phe-his) containing the amino acids 1-9 that are converted from angiotensin i/ii peptide.angiotensin i is formed by the action of renin on angiotensinogen, which has 12 amino acids and is an α-2-globulin produced constitutively and released into the circulation mainly by the liver. renin cleaves the peptide bond between the leucine (leu) and valine (val) residues on angiotensinogen, creating the ten-amino acid peptide angiotensin i. angiotensin i is converted to angiotensin ii (aii) through removal of two c-terminal residues by the enzymeangiotensin-converting enzyme (ace), primarily through ace within the lung.angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. angiotensin also stimulates the release of aldosterone, which promotes sodium retention in the distal nephron so that drives blood pressure up.figure1 formula of angiotensin i/ii (1-9)
references	1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9. 2. Richard A. Preston. et. (1998). “Age-Race Subgroup Compared With Renin Profile as Predictors of Blood Pressure Response to Antihypertensive Therapy”. JAMA. 1998;280(13):1168-1172.3. Williams GH, Dluhy RG (2008). "Chapter 336: Disorders of the Adrenal Cortex". In Loscalzo J, Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL. Harrison's principles of internal medicine. McGraw-Hill Medical.

H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH Preparation Products And Raw materials

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