Proguanil-d 4 (hydrochloride) is the deuterium labeled Proguanil hydrochloride. Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil ( HY-12784 ). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor .
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