Dibenzothiophene

Overview

Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with a K m of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone ( HY-114740 ). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Aryl Hydrocarbon Receptor

Product Information

• Catalog No.: HY-B0973
• CAS No.: 132-65-0
• Molecular Formula: C12H8S
• Molecular Weight: 184.26
• Purity: 99.92%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 3.75 mg/mL (20.35 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source