Other grades of this product :
| KP372-1 Basic information |
| Product Name: | KP372-1 | | Synonyms: | KP372-1A;10H-indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one;KP372-1;Akt Inhibitor (KP372-1);KP372-1 USP/EP/BP | | CAS: | 329710-24-9 | | MF: | C10H4N6O | | MW: | 224.18 | | EINECS: | | Product Categories: | | Mol File: | 329710-24-9.mol |
| KP372-1 Chemical Properties |
| density | 2.01±0.1 g/cm3(Predicted) | | pka | -3.26±0.20(Predicted) |
| KP372-1 Usage And Synthesis |
| Uses | KP372-1 is a specific Akt inhibitor that demonstrates at least 10-fold selectivity against a panel of additional kinase targets, including CDK1, ERK1, GSK3β, LCK, MEK1, PKA, PKC, and S6K. By blocking Akt signaling, KP372-1 has been shown to inhibit proliferation and to induce apoptosis of thyroid cancer cells. |
| KP372-1 Preparation Products And Raw materials |
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