Oxiconazole (Ro 13-8996) is a broad spectrum anti- fungal agent which can inhibit the growth of Candida , Aspergillus and Trichophyton . Oxiconazole is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin ( HY-B0272 ) in a competitive manner. Oxiconazole exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest.
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